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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2fe522f3eda93a34906c35544a55725ef2712536d3cf2c13ef9f2d251d16a1' 
  AND token = 'v5Ww+N4t1aZCIPH0VqflRKMlHdXqtzLpNNVWd/b0aSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}