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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1c9786b193cff126b7664ef4fe317ccb2b5367221e2b1f4c1addfb073d6eeb' 
  AND token = 'gl2UtgdzCwASnqC5yEoM/InReUYe1EnBv1ANRHglTJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}