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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e47a62f02db9b534e2b6e38e5437d49dab69a5a8c03de236366cdc2f8e61d7' 
  AND token = '5Xv9iVq7FXv9RT4S5uTTg7nQDgJpSJKWmIWoKAtr8iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}