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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e34760c7396c555e6acb4f5643c1fc739c75ea3665dc1f1d603aeec27a5885' 
  AND token = 'YwMAyF1/A7EUwCL8GAc4L0OQ5iaP0DZx5+XLFqf7dW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}