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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a2ade8a8366ec38696cf5153a5623d95e78f7a2a6d039705cc6235cc2c2ac2' 
  AND token = 'jRGaK6Df+P6qLUffOdxeH+VwQYosPhObG8Tes37h8iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}