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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14bdd16ec5ea01df2155e8e620988072e51b9acc9be9be4df12e2d998522d96f' 
  AND token = 'w8w96MXpiQBzmFB5tj3wAtTVWRK1G26rqte0yj+425Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}