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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d8d3b6fd860f24ee23237a03e79289125d64b0f0056abad0465749244e7d92' 
  AND token = 'iSUlj7bpf0aS0PwjFj/tu+wTngXRXmVCEnVV4iakpQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}