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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fe08688d72a23935481a35e58ec6b43e9a4865f8bbd1bc9f962dc4fc274f4dc' 
  AND token = 'vuTshVcUFtVirqT8qC0d6edfERbfEAQ7ZexgKyHlnKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}