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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436f4753ed351e5e898d80aece235e12f3102e34ced26578059540edd5bd2587' 
  AND token = 'dEgy4Abiy4l5wcWhO+aIum+ZTyEGKOWgasnF+O+EdX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}