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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f6a9bd3c5f125f202bbb921ac24c6f2db58b3034790a3ca9e509b78cb41a8a0' 
  AND token = 'X+Ocvh0S4KqnmkrRcp/4fBzRDFENU9kiOV1QvpUd97k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}