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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9951a0405839d53c4239990c2a7131b28c9a53fa5d2617a6510f5737f6f12d51' 
  AND token = 'HWrJ9uUAjEoCXVz37AxsqNKcq0IQ2PAzaGhLj5iGjhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}