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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcc039ecc470be11f9737c3e4e92a1f9529ea6959a0c4c536d56ce1364c90909' 
  AND token = 'BpDZuG8TzaRobTetRlpANbn4GGGemVhjU67jHTAiNUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}