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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b4401600b37f6096ba0b382d4d3e3f04257a8d4ef5b1e0cfdf7b89a3061376' 
  AND token = '+WMZUGut1TxZuRGpjvSo0dc4JQbBgtVW3WcyTutNZIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}