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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc080b67b9481f361026414036fda1c9aef7fab8692bc3925a6a2caa9d30da1' 
  AND token = 'SDJlarRPDig9TB+N47dLTpQTMm/HYF5sxozKo3qBYxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}