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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de136ce433a99a17cb52d1f4cd2839f2eacc78bdc9827f021faaf98536803cb' 
  AND token = 'LckywF8wlgfn1siiWUois221RjpMlfXFcMnimk/H3J0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}