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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d8b6982c9b4b696b58823537bbcf0f5e821312ff351ad62eb68b70a364c594' 
  AND token = 'WVSDWta41crmkRUHwAO5hQSP477evC9FW/m0wHboKLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}