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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a22b8512cc34d9c21914725e89ddf8848271011cd2f5151843452bc51c4e5d' 
  AND token = 'K4//25RivqGt5bb4h8dD75HfOubCK68WcwXlSnsfH/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}