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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe7d8da76e1651f5fa3efe10999b1c624baf25f7e65dc23e0bf90f29826fe242' 
  AND token = 'NrUuYRMcS1vA2cfAa7DE1DKbK0W8SCWHMv6W9mGR0ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}