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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81cf19a16291009b5cd1eee33faed75bba5043f977b74e2e89d36fab5cf5c5a' 
  AND token = 'LPm8yvn7OVdLSCQES2gXGiavtwFuH0m484hrf1jZBB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}