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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa36b6ed5c8316305aa42840e0d0419d8c85ab90b5ab4740206c79bcd064f046' 
  AND token = 'o1uHQ8EmIdlrzUHUyOaf2BPWGmv7u7gVP3EMghvRvpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}