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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1ac7f22086b7230bb12881a246ef075f99c1e5bdadf96c3c7c14a3ad817054' 
  AND token = '5du75tAIUeMOMZsqIDFwunQcEJJTsv74IH18Pa3Us5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}