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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8386edf7de470d8a6e732e043e8b309be6d7c9fefca75ea846e85d3687a35763' 
  AND token = 'Rbi8Kz2OPTZ3oQbZsQmgVZviA3wP81lk4AIfTP02UuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}