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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a13c59ff0677360d69daec629f510109d17e9e2f4aac9bfc8e11461c4171a7da' 
  AND token = '5wim1UR+zPqyETjZjW/qfXvaPLdtNPAZtEyKRiMlsEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}