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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '854f1a9aacfa3755d7235a205ba5ef593f7bad11979cf5089d0d198c6db2d4a5' 
  AND token = 'UuYGM8hmYKL9v54fy7EJ9CGV3F8pWaXv4gd08qKlNaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}