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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2ac6bc513a9b9db076b46f247a7cf32b44a024641619f7ef5b49dc3269bb0d6' 
  AND token = 'uB5qhWAWmolozdemWExWySuyTOfKURT2JA21xYpUVCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}