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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8063d9d35057c43e67c1f32c98c58093b1882e4f59581630a6547c6dbe4fe721' 
  AND token = 'uKHqRthQwIaVuctr2gL9L+BcSaYeEsxRNY6xikhRPUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}