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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143676082ab705d75646311c50e3e0170fdd5d6242f74744916dbd7d620e527b' 
  AND token = 'pw1gWmo+jk8ilkgDJB7u0R8ZfBZ4WltgrQ7tl8Ufe64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}