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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c5c7f077d82b14dd1ee8b3b1e4db0b974067e68087f4d23c648b45a7fcd342' 
  AND token = 'ZC3wGBoMqg7lbxNHN3NhI0S2YhUn9H0sn46eXfO+RmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}