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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29e16a4d38ec648b5991bb7b9d990f3f40505583fc1103efbe6c6183b19e828' 
  AND token = 'YaXEb6Fp6SDOE6S/RaYh5aWxu3tRGOJA0yRn9snKr38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}