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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e2bf7d2c8ffb3505195f4498ebb2b845b2856b2b0d1eebb4193ed7ccfc58af' 
  AND token = 'SpDNiPALDdpmDqsfnA6M7+ZiN0NZG6NqV9e1WKdaduA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}