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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e59519093d03c04d6c6e21bf8a84d5a0393fb83010535fee2a90e21102ed03' 
  AND token = 'q+nR0YHu68sHBubMrKBWS9f/tTbO+kD8PZTx3C71mPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}