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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66402692b091c685b4f2aacbfc7508f7e49702ab1bf98ddade216542f42fb7bb' 
  AND token = 'fzlU9P9v0RebyWQ2ex0fR+C8pj4IeKW6UwRGhu7xWGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}