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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb0468e42f22ec11094b7284fa18a7e6dd6abdb4fcda9fd0a67466addee7067b' 
  AND token = 'hNEWyeEJrGQh8pOk/KubLb7n9p5mYUZ2uxl7QRKtR+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}