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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0ef4e3e98a8f2bff7242e2decd09befcb9822a72ea8670816f05d482b883b2' 
  AND token = 'Z93Pd8dyRhFtcwDcKCkVTfkXb0XVXLuBzEVCC8osPcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}