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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4bc719522c08b4a425218c96205507dd53eabe91e674b915fcda116d380373' 
  AND token = '/ekDvgUtZFAD/nnsmypLoeI1kCifoF6t9SQzXGnodVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}