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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec652255653e787b7ab03d8bd0a8cf2adc1bc504bcb5341b1696f8d05eef639c' 
  AND token = 'M0yht3JtzsCCI1gKUEuoxftcakDmgsUCDxbe7YRxlok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}