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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb0608abe88dd2df33832e2db797662c2074b5e5664e7fab2218968e2cbdaf8' 
  AND token = 'TXXeHBFY2Kcks0ip+JS1TwGMAWVdBulsT64+aqJdXqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}