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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2509ccf50fe6590d2f6fe45208d29b04d1b01b9172e7b909b4cb0ce36be8305' 
  AND token = 'JT+aozq6OevWvGJtDkbYPLq8SgpJaemqdZdc5b5Ta1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}