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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7649cd6fcb4e3366c4e7bec1c23676492745360276742707dff986edae7f1d6c' 
  AND token = '4wv+l0SC9gN4IuycqjJnFUsGnvMkoJzTzEksymjMM1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}