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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c290fee07987fc5ad66cca82f00cc9a698c19457b5c6aa191cfc08bd3faf68' 
  AND token = 'cxG5FkctAz31g5IlQVRJ/AB2Few8C0LxNrZfJ/tyK2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}