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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1c70d898cf0441dab1a7352c108cb76b9c9cb2a7d0b863a15bb423c057c271' 
  AND token = 'C9yf9kRNw5nHz2q+p4eIaUtMHHwE96Ceqq8KP0Eo1e4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}