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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727d22b036ba4af9e30d1899cef63a3eaf631b12f3b034b9aed38b1bd4e84d54' 
  AND token = 'QW1aFYbMK2KvFzGrhsA9TsodYtLg2Rcuha1oBFSH5Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}