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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b491939a9728f015fc52c830e182b2586f217a20439d9dcee3b76122a15d66' 
  AND token = '4A8cyeCRbF9lpd2g/twrJG/PocN8lXIQBwn6C/Q7GIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}