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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe61c8790c4415a2e530e83fdf80995ab4e53691239b5c78d5a57189859a305b' 
  AND token = 'A+LwaYhdgq0D9TGe2XKFAhvh8VEwp6txGw0jeLAkvdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}