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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a08ef0b0298a90bac18a2117df5532a328c0adb7a4cecb5324bdc5da5c09252' 
  AND token = '46O2/f5sKuU/c3mCU2kFkcRY+M3UJX0BYmtaKVr3yrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}