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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0089f64b13a4d977ea277a65fcdc9544a479ce8ccce8a67222fb92504e225ca7' 
  AND token = 't6VcGfZjudhgEf8C7h+drtmHyAxd4mmeFDfEpfSzPSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}