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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20f1aa2a45773ad86a776be6ef970d2dd7390bdf6f9bb6cfab0f187de6e7da94' 
  AND token = 'GPFAUQavA3+K7VyKLhJeOkddyflJDzHfPPATlzHiJSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}