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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16613ea6b50e3fca17a44756b726d2c630841797d69b7c01205cf6348766021' 
  AND token = 'hRcxAS99uyJXhn+ChhgBDunf6PTLCUnuzpJi/2Qk3qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}