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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821ac33a1bf1f7566985c54adc4b7c11e6ffc1d620cf63b8716c550235031b0c' 
  AND token = 'odDhpdQBezIizk2f0zznYR4wTqGG5/pTvU1u33mSmbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}