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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3e54f49678b47d9185c42e2e0977bbd3af5e4412296cdfb7e5de3556f6139cb' 
  AND token = 'F5Jdd+jAou8s6ZwhCeQTCtAtj+46IGjH8u0yQoJgw2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}